Current Position:
     Senior Research Advisor
     Molecular Bioscience Division
     John Curtin School of Medical Research
     Australian National University
     GPO Box 334
     Canberra, ACT 2601
     Australia

E-mail:
     Esther.Gallant@anu.edu.au

Education:
     PhD 1970 Indiana University
     MS 1974 Iowa State University

Academic interests:
     • Malignant Hyperthermia;
     • muscle physiology and biophysics;
     • ion channel electrophysiology (esp. intracellular Calcium Channels);
     • Veterinary Anatomy.

Selected publications authored by Gallant:
Lentz, LR , SJ Valberg, LV Herold, GW Onan, JR Mickelson and EM Gallant. Myoplasmic calcium regulation in myotubes from horses with exertionol rhabdomyolysis. American Journal of Veterinary Research 63:1724-1731 ,2002.

Gallant EM, J Hart, K Eager, S Curtis and AF Dulhunty Caffeine sensitivity of native RyR channels from normal and malignant hyperthermic pigs: effects of a DHPR II-III loop peptide American Journal of Physiology Cell Physiology 286:C821-830, 2004.

Enzmann, N., E.M. Balog and E.M. Gallant. Porcine malignant hyperthermia: effects of sarcoplasmic reticulum Ca2+ pump inhibition. Muscle and Nerve 21;361-366, 1998.v

Dranchak PK, Valberg SJ, Onan GW, Gallant EM, MacLeay JM, De La Corte F, McKenzie EC, Ekenstedt KJ and Mickelson JR. Inheritance of recurrent exertional rhabdomyolysis in Thoroughbreds. Journal of the American Veterinary Medical Association 227; 762-767, 2005.

Gibbs GM, Scanlon MJ, Swarbrick J, Curtis S, Gallant E, Dulhunty AF, O'Bryan MK. The cysteine-rich secretory protein domain of Tpx-1 is related to ion channel toxins and regulates ryanodine receptor Ca2+ signaling. J Biol Chem. 2006 Feb 17;281(7):4156-63. Epub 2005 Dec 9.

Dranchak PK, Valberg SJ, Onan GW, Gallant EM, Binns MM, Swinburne JE, Mickelson JR. Exclusion of linkage of the RYR1, CACNA1S, and ATP2A1 genes to recurrent exertional rhabdomyolysis in Thoroughbreds. Am J Vet Res. 2006 Aug;67(8):1395-400.

Pouliquin P, Pace SM, Curtis SM, Harvey PJ, Gallant EM, Zorzato F, Casarotto MG, Dulhunty AF. Effects of an alpha-helical ryanodine receptor C-terminal tail peptide on ryanodine receptor activity: modulation by Homer. Int J Biochem Cell Biol. 2006;38(10):1700-15. Epub 2006 Apr 19.

Abdellatif Y, Liu D, Gallant EM, Gage PW, Board PG, Dulhunty AF. The Mu class glutathione transferase is abundant in striated muscle and is an isoform-specific regulator of ryanodine receptor calcium channels. Cell Calcium. 2007 May;41(5):429-40. Epub 2006 Oct 4.

Last updated October 2007